Mississippi Pot Roast Sliders

Mississippi pot roast sliders are stuffed with tender chuck roast, tangy pepperoncini peppers, and melty provolone cheese tucked inside sweet Hawaiian rolls.

Why this recipe works

Mississippi pot roast sliders are easily my favorite way to use up leftover pot roast. In fact, they were born entirely from using our instant pot Mississippi pot roast recipe.

Nothing beats the tangy, pull-apart tender chuck roast that the instant pot provides. All the flavors meld together in the pressure cooker creating a melt-in-your-mouth experience. Sandwich it all between soft Hawaiian rolls? You have my heart.

lifting a Mississippi Pot Roast Slider from pan

Ingredients you will need

Get all measurements, ingredients, and instructions in the printable version at the end of this post.

Mississippi Pot Roast Sliders ingredients

Ingredient Info and Substitution Suggestions

ROAST – You can make the roast using our slow cooker Mississippi pot roast (good for taking on the go) or our instant pot Mississippi pot roast (good for hosting, or as a quicker method).

CHEESE – We used deli-sliced provolone but Swiss, muenster, Havarti, mozzarella, or pepper jack are all great options as well.

BREAD – Sweet Hawaiian rolls pair really well against the robust flavors of the meat and peppers. You can make homemade Hawaiian rolls or buy them prepackaged from the store. Otherwise, you can use any type of bun you prefer.

How to Make Mississippi Pot Roast Sliders

These step by step photos and instructions are here to help you visualize how to make this recipe. You can Jump to Recipe to get the printable version of this recipe, complete with measurements and instructions at the bottom.

Cook Mississippi Pot Roast either in the Instant Pot or the crockpot. Drain and set aside to keep warm.
Preheat oven to 375 F.
Slice Hawaiian rolls in half with a bread knife to separate the tops and bottoms.
Place bottom layer of rolls into a 13×9 baking dish, they should just fit.
Layer cheese slices over the bottom layer of rolls.
Pile pot roast on top of the cheese layer.
Sprinkle pepper slices over the beef.
Place top layer of rolls on top.
Melt butter and mix in the garlic salt. Use a pastry brush to coat the tops of the rolls with the garlic salt butter. You may not use all of the butter.
Cover pan with foil and bake 15 minutes in preheated oven. Remove foil and bake another 5 minutes.
Use two large spatulas or fish turners to remove the rolls in two sections from the pan. Place on a cutting board and use a Chef’s knife to cut into individual sliders.
Serve warm!

Frequently Asked Questions & Expert Tips

Can I make them ahead of time?

Yes, these sliders can be made ahead. Follow the steps all the way to adding the foil to the pan. Store in the refrigerator, tightly covered, for up to 3 days. Before baking, remove from fridge and allow to come to room temp, about 30-40 minutes.

How do I store leftovers?

Store leftover sliders in an air-tight container kept in the refrigerator for up to 4 days.

large plate of Mississippi Pot Roast Sliders

Serving Suggestions

Mississippi pot roast sliders are the perfect party food whether it be for football, potlucks, or just as dinner. These sliders do well all on their own, but if you’re serving them for dinner and would like a side they pair well with au gratin potatoes, mashed potatoes, or something lighter like roasted broccoli, carrots, or a dinner salad.

For potlucks or larger crowds try serving them with potato chips, pasta salad, potato salad, or a tray of veggies.